Basic Information
VIS ID
TVIS10020484
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1142
End
2238
Orient
+
Integrated sequence
TTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAA
Host Sequence
Chromosome
chr1
Cytoband
p36.23
Reference genome
GRCh37/hg19
Start
8332260/8272200 (Hg38)
End
8333308/8273248 (Hg38)
Orient
+
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/1842304; hsa-mir-101-1/Downstream/593254;
Nearest TSS
ENST00000473358/Upstream/51671; ENST00000481265/Downstream/44578;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/54438, chr1-CpG: 61/Downstream/44476
Upstream sequence
caacagtgtaattattttatacaatcgtagttccagtaaaacctaagatgtgaggagagatagttacaggatattgacgtcaacctacacttgctatctg
Downstream sequence
CCTTCTTTTCTATCCTTCCTGGCCTTCCTTAACTTTTTCCCCAACCTGAGAAACAAGCCAAAAATGGGAAGAATTATAGCATGCTGCCCTCCAAGTGGGG
Target sequence
ATGTCActccacaagttcagctacccagaagctctctgaacccagtcctcttgggtttccatggaagcctcgggaggtcagcattattccccaaaggaatggggcaggaccctgttaggatgagggtcttatgagccccattcagaaaggtgagatgtgcgggcagattagagggaaaacgagggcaggagatggtctgagagattctgtttcccgaggccacctcctgaggcctgatgcccccaacattataaa
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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