Basic Information
VIS ID
TVIS10020499
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1097
End
2193
Orient
+
Integrated sequence
CTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTC
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
10697196/10657569 (Hg38)
End
10698244/10658617 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986766 ; MGC4859
Nearest miRNA
hsa-mir-339/Upstream/3590524; hsa-mir-10399/Downstream/7468603;
Nearest TSS
ENST00000635602/Upstream/696545; ENST00000422697/Downstream/44059;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/930983, chr7-CpG: 31/Downstream/121061
Upstream sequence
CCCcagctagacagaaattacagattatttacaaaagaattgaaattaaactgaccattgacttcttgacaatggaaccctgaagaaacaaactattgtg
Downstream sequence
tcgggtgataatttccagcaggcaaaactatttgaggattaagctattgtatctgaagctactgacacatagtaaatactcataaatcggggccattatt
Target sequence
TCTCAAAAGGACCTATTGCCCTAAGAAATAGCTACATTTCTCAGCTTGTGTGCTACCTCCTTAACTTCTGTGAACTTCTTGTCATTTTAGGGTTTCTTACATGGTAATTATACCTATAGTTTGAACACAAGCCTTTCAAAAAATACATCATTTGGGGGGAAATCAGTCCCAATAACAAGATGCTACTTACCAGAAGTCTAGGAACAAGGCTAATCTTAAGCAAAAAAATGTATAAGCTTTGGCTGAAGGGCAAGA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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