Basic Information
VIS ID
TVIS10020500
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1101
End
2197
Orient
+
Integrated sequence
CCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGG
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
10691234/10651607 (Hg38)
End
10692282/10652655 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107986766 ; MGC4859
Nearest miRNA
hsa-mir-339/Upstream/3584562; hsa-mir-10399/Downstream/7474565;
Nearest TSS
ENST00000635602/Upstream/690583; ENST00000422697/Downstream/50021;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/925021, chr7-CpG: 31/Downstream/127023
Upstream sequence
ATATTGAAAATCACCCATCTTCTATGTCTAGTGCTTAATTGAACACAACTAAGCAAGTTCATTTAATTGAAAGTCCCTTGAAAATCACTTGTTTTATTGA
Downstream sequence
ACATGGACAGGGCTGAGGGCTTGTCTTCAGGGGTGTGTCACATAAAATAATGGAGACACGGGTGTTAACAAGGAAACTTAAAACCCACCAGGTGGCTTAG
Target sequence
gatgcagctggaggccattatcctaagtgaatgaatgcagagacagaaagtcaaatttcaaatgttctcacttataagtgggagctaaacaacgggtacacatggacataaagataaagacaacaggcactggggactccaaaaggtggaggggggtgatggttgaaaactacctattggttactgtgttcactatttgggtgataggttcactagaaacccaaaccccagcattacccaatatacctatgtaac
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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