VISDB Viral Integration Site DataBase

VIS ID

TVIS10020501

Fusion event

HBV-PDE10A integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

2550

End

3646

Orient

+

Integrated sequence

TTCATTTACAGGAGGACATTATTAATAGATGTCAACAATATGTGGGCCCTCTGACAGTTAATGAAAAAAGGAGATTAAAATTAATTATGCCTGCTAGGTTCTATCCTAACCTTACCAAATATTTGCCCTTGGACAAAGGCATTAAACCGTATTATCCTGAATATGCAGTTAATCATTACTTCAAAACTAGGCATTATTTACATACTCTGTGGAAGGCTGGCATTCTATATAAGAGAGAAACTACACGCAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGAGCTACAGCATGGGAGGTTGGTCTTCCAAACCTCGACAAGGCATGGGGACGAATCTTTCTGTTCCCAATCCTCTGGGATTCTTTCCCGATCACCAGTTGGACCCTGCGTTCGGAGCCAACTCAAACAATCCAGATTGGGACTTCAACCCCAACAAGGATCACTGGCCAGAGGCAAATCAGGTAGGAGCGGGAGCATTTGGTCCAGGGTTCACCCCACCACACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATATTGACAACACTGCCAGCAGCACCTCCTCCTGCCTCCACCAATCGGCAGTCAGGAAGACAGCCTACTCCCATCTCTCCACCTCTAAGAGACAGTCATCCTCAGGCCATGCAGTGGAA

Chromosome

chr6

Cytoband

q27

Reference genome

Start

End

165932918/165519430 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1287-3p ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-7151-5p ; hsa-mir-5681b ; hsa-mir-5579-5p ; hsa-mir-33a-3p

Nearest miRNA

hsa-mir-10398/Upstream/6753629; hsa-mir-1913/Downstream/989924;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/183901, chr6-CpG: 363/Downstream/140964

Upstream sequence

gaatcttgctctgtcgtccaggctggagtgcagtggtgtgatctccactcactgcaacctctgcctcctgggttcaagtgattctctggcctcagcctcc

Downstream sequence

TTGAGAAATCTCATGGAGACTGAGATGAGGAGAGGAAAAAAAAAAAACCACATCAGAAGAAAAATGAGAAGGCTGAGCAGAGGAAAGATTGAAGTCCTCC

Target sequence

accattccgagtagttatgatgaaatctcacactggccagctccattctgcccacgacatgaattttccctttgtccagagtctccacgctgcagatgctcctgaccctttagtcagtagctgtctggcttacgggatcaaccgtcctggtatcccagtgtttgtgttcaagtcgccctcactttacttaataatgacagtaacgcacaacagtagtgatgctggcaattcagatacaccaagaggccgtaaagc