Basic Information
VIS ID
TVIS10020502
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1443
End
2539
Orient
+
Integrated sequence
AATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACACAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTG
Host Sequence
Chromosome
chr7
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
47716277/47676679 (Hg38)
End
47717325/47677727 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1183/Upstream/2794879; hsa-mir-10399/Downstream/9278058;
Nearest TSS
ENST00000635602/Upstream/21435; ENST00000412730/Downstream/83749;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/94550, chr7-CpG: 59/Downstream/301491
Upstream sequence
TTTACATTATAGTATTGAATAATTGATTAAGAAAGAAGTTTACATAATTTTTATCCTAAATAGTTTCAGGTCAAATACTGTTCACATTTTCTTGATCACT
Downstream sequence
caaatatttgtatttatgccctaaggctttatggaaggttgaacttaagagggatgacctaagataatctggcggatgaaatttctaagcagcaaatcac
Target sequence
gtgcttagggaaaaagcactagagagacagatgtggtttgtgcTTGTGACagtttcatgtgtcaacttgactgggctaagggatacctaggtaattggtaaaacattagttctggtgtgtctgtgagggtgtttgcagaaaagattagcatttgaatttatagatggagtgaagcagatccacTGCAAACTTCTCTACGCTCTCCTCCAAACCACATGGCACTCCTCTGTGCCGTGAGGTTTTGTCATGTTCGTT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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