Basic Information
VIS ID
TVIS10020503
Fusion event
HBV-LNCOG integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1325
End
2421
Orient
+
Integrated sequence
CGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGT
Host Sequence
Chromosome
chr12
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
76691019/76297239 (Hg38)
End
76692067/76298287 (Hg38)
Orient
+
Location type
Intronic
Target gene
LNCOG
Nearest miRNA
hsa-let-7i/Upstream/6712416; hsa-mir-1178/Downstream/3120970;
Nearest TSS
ENST00000382841/Upstream/37334; ENST00000551082/Downstream/50155;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/211888, chr12-CpG: 31/Downstream/49842
Upstream sequence
TTCCCTTCCACTGAAATTGTGAATTATCACACAGGCATTTCTACAGTTCATCTTGCTTAAGGAGGACTGTCTTTTCTGATCTAAACCACATTTCTTTCTG
Downstream sequence
TAAAGATGGACTATTATTGAATGTTCTTGACAAGAGAAATGACATTATAGAAGTCTAGAGTTCACCTAGTATGCCAACATGACTATAGCAGTTGTTAGAA
Target sequence
cctaatcccactcgaagcagccctaagaaacatcacccattatctctccataccacccccaaaaaattttcaccgccccaacatttcaacactattttgttttatttttcttattaatataagaagacgggaatgtcaggcctctgagcccaagcctgcacatatacatccagatggcctgaagcaagtgaagaatcacaaaagaagtgaaaatggctggttcctgccttaactgatgacattccaccattgtga
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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