Basic Information
VIS ID
TVIS10020506
Fusion event
HBV-LOC105375631 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1186
End
2282
Orient
+
Integrated sequence
CTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGC
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
90510882/89498653 (Hg38)
End
90511930/89499701 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105375631
Nearest miRNA
hsa-mir-12123/Upstream/9257180; hsa-mir-10400/Downstream/1705784;
Nearest TSS
ENST00000518652/Upstream/689745; ENST00000517696/Downstream/117456;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1170401, chr8-CpG: 92/Downstream/257606
Upstream sequence
CACTGTGACTAATAATAGGAAAAGAAAAATGGGGGTTGAAAAGAAATACTCTGATTTGCCTTGAGAGTTTTTTTGGTGCTTGAAATATTTCCTCGATATT
Downstream sequence
GGAAACAAAAGGATGCCTGATGAATCCAAGAACAAGAGAACTCCCAAATAGTCAAAAGTCTGGAAAGCAACACAGGACTAATTGAGAACAACAGAAAATG
Target sequence
ATTTCAATGCCTCCTTTTTGCTTTTTTCATCATCCAATTGCTCATTAAGTCCTGTGAATTTTGTCTCCAGAAATGTTTCACCTCTGCTTTTTTCTTCCTTCCTATTGTCAGGGCCTTCCTTTGAATCTTCATCTTCTGCTTTTTAGATGACTGAATTAACATCCTTACTAGTTTCTCTGTATGTAGCTATTTTACTGTCGTAGAACTTTTGCACTACTATTAATGTGGTTTTCTAAAGTTTAAATGTAATCTGGC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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