Basic Information
VIS ID
TVIS10020510
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1179
End
2275
Orient
+
Integrated sequence
GTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCG
Host Sequence
Chromosome
chr4
Cytoband
q35.1
Reference genome
GRCh37/hg19
Start
185965870/185044716 (Hg38)
End
185966918/185045764 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/106276;
Nearest TSS
ENST00000502981/Upstream/25787; ENST00000506338/Downstream/6132;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/23123, chr4-CpG: 132/Downstream/81623
Nearby gene
LINC02436(+7180) ;
Upstream sequence
atctgaggttccatttacatgaccatttccagtttgatggtctttaagtgagaagaaacaattatacaaggaagttgtgacggttaatattgagtgtcaa
Downstream sequence
gggaccaattaataatgattccataggaatcttgtgcagcacctctgcctgttctgcaatgcaatcttcctaaacaagtacgttcattttttctaactgg
Target sequence
TAGGATTGCTGTTCTGACAGCACATGCTGCATTTATGGCACTTTGACCATTTCTGGGCTCTCTGTTTGCTGCAtgccgagaccagctcggtctgggagaccataaaccagcagcactagaggaattaaagacacacacacagaaatatagaggtgtgaagtgggaaatcagaggtctcacagccttcagagctgagagacctgaacagagatttacccacgtatttatcaacagcaagacagtcattagcattgt
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
Curate