Basic Information
VIS ID
TVIS10020513
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1205
End
2301
Orient
+
Integrated sequence
TTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCC
Host Sequence
Chromosome
chr10
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
46940668/46607900 (Hg38)
End
46941716/46608948 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
LOC105378289 ; LOC107984026
Nearest miRNA
hsa-mir-1265/Upstream/1443812; hsa-mir-107/Downstream/2376564;
Nearest TSS
ENST00000439456/Upstream/2691; ENST00000600081/Downstream/2173;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/28275, chr10-CpG: 38/Downstream/26652
Upstream sequence
ccatgtacatctattatgcatcaatttaaaaaaaaaaaAAAGAAAACAGGTCAGACAACCCTCCTGCTTAAAACTCTCCAATGGTtgaaaacgttctaca
Downstream sequence
CTTAAGGCATACATTTGCTAAAGGTGACCTCTCTGCTTCCACGTTGTTAAGAAATCGTGATTTTTTTCAAAACAATCATCAGCTTTACAGTTTTTGAGGA
Target sequence
GTTGGGGGAAAGGGGGCTGATCATCAAATGAGTTGACAACATTGGGTGCATGatccaccctgcagacgttcgctgaatgtctaccatgtgctaggcactggaaatgcaaagacacaaatgtctgccttctgtaagttcacaggcaagctggtgaagaaatatttaaacaaaattatatcagcgccaggattaaatctgtgtggaatacagagCCAAGGCAAAAGAGGTAACAGTAGGATGGGTTTGttagtcatg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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