Basic Information
VIS ID
TVIS10020514
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1285
End
2381
Orient
+
Integrated sequence
CAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACG
Host Sequence
Chromosome
chr6
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
26013068/26012840 (Hg38)
End
26014116/26013888 (Hg38)
Orient
+
Fragile sites / regions
FRA6C
Nearest miRNA
hsa-mir-3691/Upstream/7440960; hsa-mir-10398/Downstream/1133738;
Nearest TSS
ENST00000381078/Upstream/13673; ENST00000613854/Downstream/3844;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/19904, chr6-CpG: 41/Downstream/6555
Nearby gene
HIST1H1PS2(+3267) ;
Upstream sequence
gatgtggtgattacttctttttttttttttttttttttttttgagacaaagtcttgccctgttgcccaggctggagtgcagtggtgtgatcttggctcac
Downstream sequence
GCATAACATCATGAGGTTCTATACAGGCAAGATCTAGGCTTGTGTCCTTGAACCTTGCATTCCCTCTCAAGAGCCAACCAATAATTGAATGATCCTATAA
Target sequence
tatggaagaacaggaattcccagctagattccatcaacattaggtttgtgaggttcatccatgctgtttataactgtggttttaattttcatttcatcgcatgtaaacctaatatcaccactttcaaaaagagtttagcatttgacccaacaattcctctcctaggtatacaaacaaaatatgtattcctatatataccaagacacatacacaggaatattcacggtattgtttatattagctgaaaaagggaag
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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