Basic Information
VIS ID
TVIS10020516
Fusion event
HBV-MIR4300HG integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1199
End
2295
Orient
+
Integrated sequence
CACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGA
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
81976309/82265267 (Hg38)
End
81977357/82266315 (Hg38)
Orient
+
Location type
Intronic
Target gene
MIR4300HG
Nearest miRNA
hsa-mir-10392/Upstream/374431; hsa-let-7a-2/Downstream/4012018;
Nearest TSS
ENST00000527297/Upstream/165224; ENST00000526305/Downstream/137598;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2824107, chr11-CpG: 25/Downstream/423228
Upstream sequence
ttacaacttacacaaataatcactcaaaatcatccttacactaaaaatgcaaaactatacaatttctagaagaaacaatagaagaaaagctatctgcctt
Downstream sequence
ggacaaacttcttaggacagcctgggtttgttcttctctcctctggaagcaggatgtccttctaagcttctcccagtaaatcacacagcccctaatatac
Target sequence
gaaagttttctgatattcctatattatttagagttttcatcatgatggtcattgaattgcgctactctttctgtatttatcatcattttttctcccttttatagttaatacggtgaattattctgaataatttccaaacaataaaccagacttgcactcctgagataagtttccctttgctattctaggttattgaattcaagttattaacattctactatgagattttgcatctatgatcataaaagctattct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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