Basic Information
VIS ID
TVIS10020517
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1178
End
2274
Orient
+
Integrated sequence
AGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCC
Host Sequence
Chromosome
chr5
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
29606883/29606776 (Hg38)
End
29607931/29607824 (Hg38)
Orient
+
Fragile sites / regions
FRA5A
Nearest miRNA
hsa-mir-10397/Upstream/12450784; hsa-mir-103a-1/Downstream/2328278;
Nearest TSS
ENST00000502646/Upstream/210795; ENST00000506396/Downstream/1585926;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/678246, chr5-CpG: 37/Downstream/1586021
Nearby gene
UBL5P1(-5921) ;
Upstream sequence
CCTCCAGGTCCGGACGCGGGGCGTCGGGCTCCGGGCACCACGAATGCCGGACGTGAAGGGGAGGACGGAGGCGCGTAGACGCGGCTGGGGACGAACCCGA
Downstream sequence
taaatagcttgaatattttttaaaaatcaaaataccttaattataaaatataGATGCAATACTGTAAAAATGTTTTTAGGGAAAAATGTAATTTTTGAAA
Target sequence
TGataattttaaataatatcattttattatatGGTGTCTGTTTTGAATAGCTTTTGTATTGAATTTTGGATTTACCAAAACATAATTATACAATCTCCTGATAAATATGGTTGTATTTAATTTTCAGTAATTCAGACTAAAactcctttttcttatctaattgctttagctaatgtctctattactgagtaaaattttactaatcataatgaacatctttgtcttattcttaacctgagtggaaaTAAGAATTTC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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