OR8B3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10020518
Fusion event
HBV-OR8B3 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1199
End
2295
Orient
+
Integrated sequence
CACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGA
Host Sequence
Chromosome
chr11
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
124270182/124400286 (Hg38)
End
124271230/124401334 (Hg38)
Orient
+
Location type
Intronic
Target gene
OR8B3
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7a-2/Upstream/1018774; hsa-mir-3167/Downstream/2587124;
Nearest TSS
ENST00000527297/Upstream/1262; ENST00000642111/Downstream/23559;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/658449, chr11-CpG: 44/Downstream/221434
Upstream sequence
gcactccagcctggccagtgaagcaagactccatcctaaaacaaacaaaCAGAGCAGTAGAGGTTGATAATCACTATTTAAAACTATGAGGTTACCCTTG
Downstream sequence
cacaatcacctcttacaggtctcgtctcttaatactgctacaatggcaattaaatttcaagatgcatttgggaggggacaaacaatcaaaacacagcaAT
Target sequence
ttaagatcattaacacacctatcaactcacatactgattttctgtagtgtaaacacttaaaatctactctcttagcaattttgaaatatatattgcattattattaactatactctccagtcagtgcaatagattccaaaaacatatacctcctttctaattaaaactttgcaccctttgaccaacatctcattcccctcacccccagcctctggtaacaaccattttgttttttTTCtttttattatacttatt
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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