Basic Information
VIS ID
TVIS10020522
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1443
End
2539
Orient
+
Integrated sequence
AATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACACAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTG
Host Sequence
Chromosome
chr7
Cytoband
p12.1
Reference genome
End
53106447/53038754 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1183/Upstream/8155906; hsa-mir-10399/Downstream/3917031;
Nearby gene
POM121L12(-781) ;
Upstream sequence
aagaaaagaaattaatactaagactatggtgacaggaaattgatagagtttgattaatattcatattgtttgaggatatcatgatagggtgatcaataag
Downstream sequence
tggactgggaaggactcattagtctggaaagagattgctcacctggtaatTCAAAGCACTATCTCAGAGTAATGTGGTTGATCAATTACCTTATGGAACA
Target sequence
gatcacttatgcagaaaatatggagaagggcaagggtgaagcctagggtactccaacatttacaacatgaaagatcggagaatggagaaagaagaaccctcaaaaccaagaaccatgagggagaaggaaatccaggagCAGCAGGGACACTGAGGATTCCAGAGCATGGAATTTATCCACCACGGTGGCTGCCTTTGAGAAGAGATGTTCTTTCCCTGATTTCAGAAGAGAAATTGTTTTAGAGTGTTGGAAGTG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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