IQCK _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10020523
Fusion event
HBV-IQCK integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1176
End
2272
Orient
+
Integrated sequence
CAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTC
Host Sequence
Chromosome
chr16
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
19851232/19839910 (Hg38)
End
19852280/19840958 (Hg38)
Orient
+
Location type
Intronic
Target gene
IQCK
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1225/Upstream/1345334; hsa-mir-11401/Downstream/1665091;
Nearest TSS
ENST00000527434/Upstream/12846; ENST00000570859/Downstream/17088;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/121295, chr16-CpG: 160/Downstream/42685
Upstream sequence
ccattgaaccagtcttccttcaactggtctccattcactctgatccatccaaatcaattctgccaagatactcataacacaaaagaaagcatattatttc
Downstream sequence
CCAAATTGTCCCTGCTTCTCTCTGTGAGCACCAGTCCAAGGCTGTTGACACATGGTGTTCACCCTTAGGATCTAAATTTAGGATGTGAACAGCTAAAGCG
Target sequence
cttaaagctcaggaggttgaggctgccgtgagctatggttgtgccactgcactccagcctgggagacagagcaagaccctgtctccaaaaaaagaaaaataaaGCAAACAGAACTGTTTCCAAAAAAAAAAAAAATTAAGGGaagatatatgcttacatataatatataaatggataaagaccgcctgtaatctcaggactttgggaggccaaggctggtggatcacctgagatcaggagttcaagaccagcctg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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