Basic Information
VIS ID
TVIS10020525
Fusion event
HBV-LOC105369720 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1325
End
2421
Orient
+
Integrated sequence
CGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGT
Host Sequence
Chromosome
chr12
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
30775959/30623025 (Hg38)
End
30777007/30624073 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105369720
Nearest miRNA
hsa-mir-1244-3/Upstream/4748946; hsa-let-7i/Downstream/11699627;
Nearest TSS
ENST00000382841/Upstream/302191; ENST00000500076/Downstream/13076;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/421346, chr12-CpG: 68/Downstream/71257
Upstream sequence
GGGAGGCTGGCAAAGTGCACATATAATTCTGATCCTTAAGAACTGAACTTgactgggtgccatggctcatgcctgtaatcccagcactttgggaggctga
Downstream sequence
ttaggacgtagacatctttgcgtgtttgggggtcgtggttcgggagtcactattctgcttaccgcaGCCTATAATACAGCAGCCAATCACAGGACAACCA
Target sequence
AGCAAAGAATAATTTATCCGCAGTCACACATCTCTCTAGATGCAAAGTGCTAGTGTGTCTCCTACCtcagttagcgttctacgttcattgtaagcaacagcagccagctctagctaatttaagtagaaaaggaactcaatgaaaggatcctaggttctcacagaaCTAAAAGGAAATCTTACAAACAAGGCTCAGAAACTGTCAGGATATTTGCTGAATGATTAAAGAGATATTTGATAAATGAAAATATTACAT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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