Basic Information
VIS ID
TVIS10020526
Fusion event
HBV-LOC105378410 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1205
End
2301
Orient
+
Integrated sequence
TTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCC
Host Sequence
Chromosome
chr10
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
88952636/87192879 (Hg38)
End
88953684/87193927 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
LOC105378410
Nearest miRNA
hsa-mir-1265/Upstream/928091; hsa-mir-107/Downstream/309954;
Nearest TSS
ENST00000439456/Upstream/97683; ENST00000381707/Downstream/31521;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/97138, chr10-CpG: 27/Downstream/29009
Upstream sequence
AAGATAGAAAAGTTATCATACTTATCACGTTGTCATATAGGTGGAACAATTGATGCTCTAGCTGATTCAGACAACAAGAATTATGAGTAAATTTAAAGGT
Downstream sequence
TTGTTATTATGAAGTGAATTCTACCCACTTAAGGCATACATTTGCTAAAGGTGACCTCTCTGCTTCCACGTTGTTAAGAAATCGTGATTTTTTTCAAAAC
Target sequence
CTTAGTTTCCCCAAAGGTATCCTTTTTCTAAAAGCGTTAGAGGCATTCACCTTTCTCCCCACTAGTAAGATCTGTGCTGTTTCATTTTACATCTTTTTTTTTTGGTTGGGGGAAAGGGGGCTGATCATCAAATGAGTTGACAACATTGGGTGCATGatccaccctgcagacgttcgctgaatgtctaccatgtgctaggtactgggaatgcaaagacacaaatgtctgccttctgtaagttcacaggcaagctgg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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