Basic Information
VIS ID
TVIS10020530
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1179
End
2275
Orient
+
Integrated sequence
GTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCG
Host Sequence
Chromosome
chr4
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
30427724/30426102 (Hg38)
End
30428772/30427150 (Hg38)
Orient
+
Fragile sites / regions
FRA4D
Nearest miRNA
hsa-mir-12113/Upstream/1606434; hsa-mir-1243/Downstream/5999216;
Nearest TSS
ENST00000502981/Upstream/1211704; ENST00000507864/Downstream/293265;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/147637, chr4-CpG: 75/Downstream/290081
Upstream sequence
AAAGCATTTTTCAGCAAGTAGTATGAGGAATCCTAGCTCGTAAAATAAAACTGGCTTTTTAAACTTTAGTATGTCTTGAACATTCAGATGTAAAATATAT
Downstream sequence
AAAAACTATATTCTAGTATAAAAACTATTAAAGATGCTTAATGTCTCAACCTTGAATTTACATGATTTTTAAATATTCTTGTGAGTAGTTATTTTTAAAT
Target sequence
TACAATTTTTAACATGCTTTTTTCTTTAAAAAATGTGTACACCATTTTAAAATAATTTGAAAGAAACAGCATCTGTTACTTTCCTCAGAAACTTATCTTTCCAAATTTATAGCACGCATTGATTTTTTTTTCTTTATGAACAGCCACTTTCTTTAGATTCTTGCAAGCTTTTATGAGCATCACCAGTTCAGTTTCCTTGGGGTTCTGATCTAAATGTTTTCATTTCTGTGCTATACTGGATATGATAACCTCAAC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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