Basic Information
VIS ID
TVIS10020531
Fusion event
HBV-UNC79 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1159
End
2255
Orient
+
Integrated sequence
AACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGA
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
GRCh37/hg19
Start
93816867/93350521 (Hg38)
End
93817915/93351569 (Hg38)
Orient
+
Location type
Intronic
Target gene
UNC79
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1260a/Upstream/16084231; hsa-mir-1185-1/Downstream/596657;
Nearest TSS
ENST00000550708/Upstream/3330; ENST00000555664/Downstream/78768;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/2756, chr14-CpG: 45/Downstream/78902
Upstream sequence
TCTTCCTCGTTTGGGAGAAAGGATCAATGTTCCCTACAAAACGCTAAGTTTTGCATAAAGGTGAAACCTACATATACTAGGGTATAGAATTAATTTAATT
Downstream sequence
ggCTAATGTTTTGTTACTTTAGTATTTTTACATTTCTATCTCAAAATTTATATTGAtgtattagttgatgttctccgtagaaacagaaaaaataggatgt
Target sequence
aatttataaaaggaacgttgtaagtaattaagttggttataattaaaaaggaaaccattataatagtctttctaaaggttagccccttacattaaaacaggggttacttaaggtattgctttgcttttagggaaattacaagaggttttgatttttaattatataaccaatttcttttaaaaacttcttagattcgtatctcagaggttcaacatttgttgtgtcttgttgctttcagcttttcctccccttgag
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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