Basic Information
VIS ID
TVIS10020541
Fusion event
HBV-LINC00314 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1161
End
2257
Orient
+
Integrated sequence
CGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACG
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
29391699/28019380 (Hg38)
End
29392747/28020428 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC00314
Nearest miRNA
hsa-let-7c/Upstream/1065337; hsa-mir-3197/Downstream/2354866;
Nearest TSS
ENST00000624081/Upstream/6017; ENST00000412526/Downstream/149715;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/875393, chr21-CpG: 29/Downstream/864675
Upstream sequence
gagcgagagtgcagggaggttttcccaggcctccaagagtgtgaggatgcctgagtctgcagccgctgtttgggcagttgcagctgtgcctgggagtggg
Downstream sequence
ttagtagagacggggtttcaccatgttagccaggatggtctcgatctcctgacctcgtgatccacccgcctcggcctcccaaactgctgggattacaggc
Target sequence
gcaggactcctgcctgctccacggagcgaggctgtgtatgcagctgtggtttgggcagctgcagcagcacccggggagctaccaccccaactcagaaggggtggggctccagcttgtccatggtcccctggctccacacagtaggcagccccaaccgcacctccctgctccagccgggtgatggcagtggcAGGTTGTCTGGAGGGCTGCTACCATCACAGGAATCAAATGAAAGTAAAAGTAAGCCATAGTGCT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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