Basic Information
VIS ID
TVIS10020542
Fusion event
HBV-LOC101927947 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1179
End
2275
Orient
+
Integrated sequence
GTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCG
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
154857951/153936799 (Hg38)
End
154858999/153937847 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC101927947
Nearest miRNA
hsa-mir-12113/Upstream/1400283; hsa-mir-1305/Downstream/5190955;
Nearest TSS
ENST00000502981/Upstream/147679; ENST00000625026/Downstream/204275;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/143711, chr4-CpG: 39/Downstream/395131
Upstream sequence
ttagcccaggcatggtagcgggcacctgtaatcccacctagttgggaggctaaggcaggagaatcacttgaaccctggaggcagaggttgcagtgagttg
Downstream sequence
TTAAGTTTAATCCAAGATCCTATTGGGAAGGGGTTTTAACTTCTTCCTTTGGAGAGTGGTGTGGTCACCTTGGCTTGTTTTGTTGTAAAGTGAACAGTGA
Target sequence
GAATTCTAATTTAATGATAACACTTAGTACTTCATAGGCTTGTTATGTTTCCTATTCTCCCAATGTAACCAGATCTGTGATggggcagtgtggtggagtggaaagaccatggctttggtaccagatagatctctattcacattcctgtaacaacacttaccagtggtgtaatgttttgagcaagttatttaacttctattattttcattctcttcatttatgtaatagagacaacaatatcatgtaggcttttta
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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