Basic Information
VIS ID
TVIS10020543
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1176
End
2272
Orient
+
Integrated sequence
CAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTC
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
22179525/24599561 (Hg38)
End
22180573/24600609 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1-2/Upstream/277815; hsa-mir-122/Downstream/1990858;
Nearest TSS
ENST00000575820/Upstream/81555; ENST00000583558/Downstream/27573;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/172518, chr18-CpG: 113/Downstream/748606
Upstream sequence
ACAGTGTGTTAActtgagtccaggagtctgaagctgtagtgcactatgactgcatctgtgtgtgtgtgtgtgtgtctgtgtgtgtgtgtctgtgtgtctc
Downstream sequence
TGACACGTGTTGTGAACAGAGGGTTAGAATTACTTCATTTTCTGCACCTGAGACCCTCTCAAAAAATGATCACCAATATGCATAGATTACATCCACCTAC
Target sequence
gactttgttttgttcactgaaaagtctgcaccactgacaaccatgcagggtgcacaataggtgctcaataaatatctgttgaatgaatAGACGGGCATCAACTAGTGAGAGGCAGAGACTGCAGAAATGAAGGTGAGCAAAAGTCTTCTGCTATCATGGAGCATTTAGCCTAGTGAAGGAGTCTTGCATTGGCAATCAGGTGGGTGTGATACATTCTATGAGAGGAATTACAAGAGGTCACAGAAGTGTACAACA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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