Basic Information
VIS ID
TVIS10020545
Fusion event
HBV-chr8 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1186
End
2282
Orient
+
Integrated sequence
CTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGC
Host Sequence
Chromosome
chr8
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
108211409/107199181 (Hg38)
End
108212457/107200229 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12123/Upstream/2714716; hsa-mir-10400/Downstream/5443264;
Nearest TSS
ENST00000518652/Upstream/428936; ENST00000520037/Downstream/95312;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/540818, chr8-CpG: 92/Downstream/882398
Upstream sequence
AAAGTCCAGCTCACACCTCTGTCAACTCCCTGTATAATATGACTTCCAAAAAAACACCTGTGGTTTGGTtatacatatatatggacatatatatgttata
Downstream sequence
AGACTACTATTGAAAGGATATTGTAAGTAAAGATTTGGGTCATATTAAACATGATATAGGCACAATTAGTGTTCAATAAATGACGATTGTCTTTCTTTTC
Target sequence
TTCACACAACTATATTCTAGTCAGCCACTATCAGGCTTAAGGCTTATCAACTCTGTATAGTTAGATCATTTGTGTTCCATAAAAGACTGAGGCTAATTACCCTAAACATGCAATTCTAATGTTTGTTAGAGAACTAGAGCTCACTAATATCCAATTTGTTTTCAGTTAGAGAAAATGGAGTCTAcagtcactctgcattcctcttacctaattctagaaaaattctaacctacttctatctttatagatttatct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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