VISDB Viral Integration Site DataBase

VIS ID

TVIS10020546

Fusion event

HBV-ERCC6L2 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1171

End

2267

Orient

+

Integrated sequence

TCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCT

Chromosome

chr9

Cytoband

q22.32

Reference genome

Start

End

98666260/95903978 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-3162-3p ; hsa-mir-6771-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-7154-3p ; hsa-mir-5004-5p ; hsa-mir-383-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-3714 ; hsa-mir-122-3p ; hsa-mir-1915-3p ; hsa-mir-1976 ; hsa-mir-2276-3p ; hsa-mir-3194-3p ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-4726-3p ; hsa-mir-5001-3p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6764-5p ; hsa-mir-6778-3p ; hsa-mir-6791-3p ; hsa-mir-6796-3p ; hsa-mir-6829-3p ; hsa-mir-6836-3p ; hsa-mir-6840-3p ; hsa-mir-6890-3p

Nearest miRNA

hsa-let-7a-1/Upstream/816836; hsa-mir-12126/Downstream/1459576;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/26767, chr9-CpG: 122/Downstream/116956

Upstream sequence

GAACACACTTGAATTCATATCAGTTCTGGGATTTTCGTAACCATCAATCATAAAGTCATAGTAAGAAGAAGAATAAAGCGATATCAGTGCAGTTGAGGCA

Downstream sequence

CAAAGGACTTGGAAGAGCCCCTGACTACAGTGGATTCTAAACTGAAATTTCTGTATATGAAATAACTGCAGCATACTGAAGGAGAAAATGATCAGCTATA

Target sequence

CCCATGTAGAGTCAGCTTTGAATTATTTATTGATTTTTTAAAAATGTTTATGTGGTTACATGTATTGGTCTGtatagtttctgggttttatgtttgcctagaaaagccttttgtactctaaatttataaatacattcattcatggttcttttataatatgtgtgattttattttatacctttatatctttgtttcagctagaatttattttgctgtaggtgtctagtaatccaattttattttcctcagttggtt