Basic Information
VIS ID
TVIS10020549
Fusion event
HBV-chr15 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1142
End
2238
Orient
+
Integrated sequence
TTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAA
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
25187739/24942592 (Hg38)
End
25188787/24943640 (Hg38)
Orient
+
Location type
Intronic
Target gene
SNHG14 ; SNRPN
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1268a/Upstream/1380461; hsa-mir-10393/Downstream/905107;
Nearest TSS
ENST00000557528/Upstream/85991; ENST00000577949/Downstream/11287;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/64031, chr15-CpG: 77/Downstream/11248
Upstream sequence
acaaagctccaggccctaactgtgctctctggctccccgtggcctccagacttcccctcgggctcctgccgctctctggacctctctgggatgtgtaagt
Downstream sequence
gcccagtagcaggccaacagctgtttctcaaaaggagggtagttaactacagaggatagcagggctttgctccaatatcctaaaggcctatgctgcaact
Target sequence
agggaacttttgacagaagcattgcatgcagtgtaagcaaatctgtatccagagtaagcatctgttctagtcaggacaaaacactggcccttccatgatggaggggattcagtgtaatcaacctgccaccaggtagctacctgatcactgtggggaatggtaccatagtggagactcagtgttggtctctgctgagggtagattgggcactcagtggtggccatagttaggttggtcttggtgaatgggagttca
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
Curate