Basic Information
VIS ID
TVIS10020551
Fusion event
HBV-chr16 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1176
End
2272
Orient
+
Integrated sequence
CAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTC
Host Sequence
Chromosome
chr16
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
18077805/17983948 (Hg38)
End
18078853/17984996 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1225/Upstream/1615006; hsa-mir-11401/Downstream/359017;
Nearest TSS
ENST00000527434/Upstream/11406; ENST00000549796/Downstream/166599;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/512943, chr16-CpG: 18/Downstream/352312
Upstream sequence
CAGCCTCTCCCCACACAAGGGTTTTGGGACCACCAAGCCTTCTTTGGGGTTCTTGAGGTCAATCAAGGCTGCCCTTTAGTGGGGGATGAGCAGAGTGGCC
Downstream sequence
ACATGTTGCAAGGATTTCTGGTGTGCTTGTAAACCTAAAACCGTAATTGCCAAAGAGAACTCGTCTCCCACAAATCAAACCCCTCTGTATTGACAATTAC
Target sequence
accttaggaagcaggtgcttggagcagatgccacaggtggcctcacccgtgtcactgcagggcacacaggttcaacttccagtctccagcacctgcgtttctttgccagggctctctcgggctggtgaaacttgctttatcctcatgtgacaagctgtgccacccctgctccggggacatccttcaacagatgaccagtgccccaggtcactcgtctctcctgaagaactatgagttgtgagttacacaatatct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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