VISDB Viral Integration Site DataBase

VIS ID

TVIS10020552

Fusion event

HBV-TRDMT1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1205

End

2301

Orient

+

Integrated sequence

TTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCC

Chromosome

chr10

Cytoband

p13

Reference genome

Start

End

17219693/17177694 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1227-3p ; hsa-mir-648 ; hsa-mir-595 ; hsa-mir-5692a

Nearest miRNA

hsa-mir-1265/Upstream/2739985; hsa-mir-107/Downstream/667413;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/358670, chr10-CpG: 49/Downstream/23611

Upstream sequence

CCATTCTTCCTAAGGGTAGGTACCTCTGGAGAAGAAACCCAGCGATTTGGCCCGGTAGGCGCCCCATTCCCAAGACAGTCCCACAGAGCTGACTACTCAC

Downstream sequence

TTACAAAAATAGACAAGAAacacacacacacacacacacacacacacacacagacaTTTGAATAGCAATACTTTCCTTTCTTTTTCTGATGATTCTTCTT

Target sequence

GATATTACTGACACTAATTCAACTTGCCTTCTCAAAATAGAATTGGGGGGTGGTTATTGTTTCTAAGGAAAAGGTTAAACTTACAGATAAGTTTTAAAAAGCAAACCTGTCAATTCTGTCAAAATCTTAACTTGAATTCCAAAGACTAGTTGCCTTGATATTTCTTAGTATACAGTTTAAATCTACAATCTCCAAAATTCTTTACTTTTAAGTTACATATATAGATTTTGAAAATGTATAATTAAAAATGTCAAA