Basic Information
VIS ID
TVIS10020555
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1285
End
2381
Orient
+
Integrated sequence
CAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGGCCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACG
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
85257366/84547648 (Hg38)
End
85258414/84548696 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/6008339; hsa-mir-1202/Downstream/5764046;
Nearest TSS
ENST00000381078/Upstream/72719; ENST00000591225/Downstream/7456;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/319638, chr6-CpG: 129/Downstream/214288
Upstream sequence
gatgtgtttttttcttgcttttccagttccttgaggttcattgttatattgttaatttgtaatgtttctacttttcttaggtaggtatttattcctataa
Downstream sequence
atctgtcctcctcgtacttccaaagtgttgggattgcaggcgtgagccacggcacctggccTAATTTTTCTTTCCACTGGGTAACTTTAATCTGAGTATC
Target sequence
TTCAGTGACTAACATTTCAAAACCTTATCTGTGGCTGGCAGGCCATGTTTCAGTTTTGTCAGAGCCCAGATATAGACTGTGTGGTTTTCTGATGATATATCTCTGTAAGATTTGTGGAATGCTAAAGATGGAGTTGTCAACACTACTTTATGGCACCTCGGTGCATGTCAGAAAATGAAAATATTTTCAGAAGTGTTAGCATTATTTTGACTGATGATATACTCTTTTAAGACAAAGACTTATTTAAATAAAAAA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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