Basic Information
VIS ID
TVIS10020558
Fusion event
HBV-LOC105374655 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1178
End
2274
Orient
+
Integrated sequence
AGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCC
Host Sequence
Chromosome
chr5
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
12418087/12417975 (Hg38)
End
12419135/12419023 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105374655
Nearest miRNA
hsa-mir-10397/Upstream/1939830; hsa-mir-103a-1/Downstream/2406906;
Nearest TSS
ENST00000502646/Upstream/513932; ENST00000505877/Downstream/155614;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/513384, chr5-CpG: 46/Downstream/375837
Upstream sequence
ATAATCATGATATTCCAATTTAAAAGCATATAGCCAGAGCTTTATATATGAAAAAAGTGAATAGTTGACCTACAGATAGCCAAGAGGGAAAAACGAGTTA
Downstream sequence
tacacatcttctcatAAAgaagtggccagaaagaacttaggcaaattcctaccacaatgtctattcactacctgcatttatgcatgaattcatatcttta
Target sequence
atccctgctccaaactccagcatcatgcgatattcccatgcatcaaatctatacatgtacccactctatctaaaagttacaactaaaaataaaaTAAAATTTCAGGTAAAAGAAATAAAATGCTTAGGCAAAGCTTAATTTCCatttttaaaaaacattatttttgattattaaatttaatgttatatttCAAATATGTACTTTGTGGCTCCTCAAAGATTCCTGTTTGTTAGATCTTTCAACTTTTgacctcca
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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