Basic Information
VIS ID
TVIS10020559
Fusion event
HBV-chr16 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1176
End
2272
Orient
+
Integrated sequence
CAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTC
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
59656873/59622969 (Hg38)
End
59657921/59624017 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1225/Upstream/1850617; hsa-mir-11401/Downstream/7578304;
Nearest TSS
ENST00000527434/Upstream/742756; ENST00000568279/Downstream/231336;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/888545, chr16-CpG: 19/Downstream/130871
Upstream sequence
ACCCCATGATGTAGCTGGAGTTAAGTGCTTACATTGACTTATTCAAgccaggctctgtttgagtgctttgtaaaatttcactcattgagccctcaaaatg
Downstream sequence
agaatagtttccccttcccatactcgcagtccagacatggcaatagccaatttccaaagtcctgggtgttctgggctcagaatggggagtatcatacgag
Target sequence
gcttcagccggtccctctgtttggggttcctcacttcccaaaacatctctccctttttttttatataaatgtgccatggcgatgaaggtttgttcgttctctcgattttgatgcaggattctttgactggtctggcacactaaaaacaaaccgattaaacagagaaacgtaattccaaaatttactacagtggagccccaatagacttaattcaagtcgtggggtttaatccataaagattttctgccacctgat
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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