VISDB Viral Integration Site DataBase

VIS ID

TVIS10020560

Fusion event

HBV-ACSM2A integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1176

End

2272

Orient

+

Integrated sequence

CAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTC

Chromosome

chr16

Cytoband

p12.3

Reference genome

Start

End

20473676/20462354 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-18a-3p ; hsa-mir-3184-3p ; hsa-mir-6818-3p ; hsa-mir-6888-3p ; hsa-mir-6873-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-3120-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-3615 ; hsa-mir-6812-3p ; hsa-mir-216b-5p ; hsa-mir-6807-5p ; hsa-mir-8055 ; hsa-mir-6844 ; hsa-mir-3191-5p ; hsa-mir-6758-3p ; hsa-mir-5571-5p ; hsa-mir-4742-3p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-218-2-3p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-4320 ; hsa-mir-4797-5p ; hsa-mir-526b-5p ; hsa-mir-6847-5p

Nearest miRNA

hsa-mir-1225/Upstream/1966730; hsa-mir-11401/Downstream/1043695;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/112130, chr16-CpG: 65/Downstream/278970

Upstream sequence

gagactccagtaaagacaggtgtaagaaattataaaagtattaatttggggaactaataaatgtccatgaaatcttcacaatttatgttcttctgccatg

Downstream sequence

agttggtttcaggaagagactgttgtcatccttgctttaaagttaaattataaactaaattcctcctatagttagcttggtctatgcccaggaatgagca

Target sequence

AGGTTCAACATTTTAAAATTGAAAATTTTCAAACAGAAATTTAGATTTCTGGATTTTTTAAAGTTATACTTCCTTTAAATATTGAGGAAGGCCCTTTAAATATTCAGGAAGGCCCTTACTACCATGACTCACCATTCTGAATCCATAAAAGtaaatttgctatataaacatcaaaaaatatttccattcacaaataacaccattagcaaaataaatgactaatgaaaaccatggagaaaatattcaactcatata