VISDB Viral Integration Site DataBase

VIS ID

TVIS10020562

Fusion event

HBV-FGF14 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

987

End

2083

Orient

+

Integrated sequence

TGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGCTATCCTGCCTTGATGCCTTTATATGCATGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGA

Chromosome

chr13

Cytoband

q33.1

Reference genome

Start

End

102579873/101927523 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-8068

Nearest miRNA

hsa-mir-1297/Upstream/2283326; hsa-mir-1267/Downstream/40119;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/9350, chr13-CpG: 60/Downstream/466807

Upstream sequence

CCTGCTCCTGCTTCCTAGGCTGCTTTACTCCCCTGCTCAGTGTTACCTGTTATCATTTGCTGGACCGCTCCAGTACCACCTGCTTACCTGAATTTCTTAT

Downstream sequence

GAGACAGCAGTTTTACATATTTGTACTGTACAAAGTTTAGATCTGAGCCCTTGTTGCCCTGCTGCAAGAGTCAAAGCTGATACTCAAATACTCTAATTCC

Target sequence

AACTTTAATTATTGCATCGCTCAGAAAAAAACGTACAGCAATTCTCAGTGATTGTGGAGACAGGACCATTAGGCTCCCCAGTGAATTGTGAGAATGCATTTTTCTAAGCCCCACATAAATCCATGAAGAATTTAATTTCTTGAGTTTATAACATGCCTTTCATGAGATTTAAGGCCATAGAATCTAGCTAAATAAAACTAAAGCTAGACATGTGATGCTTTACAAAATGAGATTTGGGGCCTAAGGCTATTGCCA