Basic Information
VIS ID
TVIS10020563
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1179
End
2275
Orient
+
Integrated sequence
GTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCG
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
GRCh37/hg19
Start
39044477/39042857 (Hg38)
End
39045525/39043905 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/174730; hsa-mir-1243/Downstream/368005;
Nearest TSS
ENST00000502981/Upstream/9935; ENST00000514399/Downstream/1134;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/174698, chr4-CpG: 93/Downstream/661
Nearby gene
KLHL5(+1817) ;
Upstream sequence
AGTGGACATAAGGCCTTTAGTGGCCCACTGAAGAGATACCTAATTCAGGCTGGGTGTATGCTTGTGCAGTGGGAAGTTAGTCTGGGAAGGATTACAGTAA
Downstream sequence
ATGACCACATTCAACCATCACGGACGGAGAGCATACAGCTAACTCAGAGTAGCAAACACTAATCTACGAATAATGAACATAGGCATTATTTTAAGAACCA
Target sequence
TGCCTAtttctttctttctttattattattattattattatttagatggagtctcactctgtcaccaggctggagtgcaatggcacaatcttggctcaccgcagtctccacctccctggttcaagtgattcccctgcctcagcctcccgagtagctgggattacaggcacgtgccaccataaccagctaatttttatatttttagtagagacggggtttcaccatgttggccagaatggtctcggatctcctgac
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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