VISDB Viral Integration Site DataBase

VIS ID

TVIS10020566

Fusion event

HBV-NOC3L integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1205

End

2301

Orient

+

Integrated sequence

TTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCC

Chromosome

chr10

Cytoband

q23.33

Reference genome

Start

End

96101794/94342037 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-3926 ; hsa-mir-4753-5p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-6768-3p

Nearest miRNA

hsa-mir-107/Upstream/4748162; hsa-mir-1287/Downstream/1722278;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/346545, chr10-CpG: 39/Downstream/20746

Upstream sequence

AGAGAACAATGTCAAGCCAGGGGATCCACTGGTTGGCAACCAATGGCATAGGTTTGCTTGATCTTTTAGTGTTCAGTGGTACCATCAACtatatatatat

Downstream sequence

GAAAGTTTAGGAGGTATCCGGCAGGATCGGCTTCTAAGAAAACAGGTGGTGGGAAGAGAGACAAGGAAAGATTCTGCTACTTACAAGAATATGGACCTTA

Target sequence

aaaaaaaaaaatttctacaaaaaaatagaaaaattagccaggtatggtgccccacatctgtagtcccagctactcaaaaggctaaagtgggaggatcacctgagccctggaaggtcaaggctgcagtgagctgtgattgcaccactgcactccggcctgggcaactgagtgagaccctatctcaaaaaagaaaaaaaaGACCTATAAAGGTTATCTTTAAGATAacctagtatgaggcagatttacagggtgact