UNC13C _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10020568
Fusion event
HBV-UNC13C integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
885
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chr15
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
54913975/54621777 (Hg38)
End
54915023/54622825 (Hg38)
Orient
+
Location type
Intronic
Target gene
UNC13C
miRNAs that regulate target gene
hsa-mir-128-3p
Nearest miRNA
hsa-mir-10393/Upstream/2344577; hsa-mir-11181/Downstream/750115;
Nearest TSS
ENST00000557528/Upstream/10302; ENST00000569661/Downstream/433922;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/861970, chr15-CpG: 52/Downstream/573719
Upstream sequence
GGCTCCAGACTCAAACATGAGAGTTGTGTTATGAACCACTCTTAAAGTTCACTGCAGTGGGATTGACGGTGATAGAGATCTCTATCCACATGTAGGGGTG
Downstream sequence
ACATTGTAAAAACAGCCTGAATGCAGGGGTAATTTCAAAGATGAAATTAAAGGATTAGCATTTTGTTAACAATACGCTCGTTCTATTTTTATATTAGTCA
Target sequence
aagtttaacccctGACTAATCTTTTCCAGGAGACAGTTGACTTTTTAAAATGCTATCGGTACACcttataaataaattgttgtaatatatttgcatgtggggctcccctggccaactatgagtttcatgaaggcagggaccctaacaaagctacctttctgttcccagtgctccggtatggcacattgtggAAAAGCTCTTAAAGTAATAAAAAGCAATGGTGCATCCTTGTGTGCAAGAAATGAATATAACTTC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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