Basic Information
VIS ID
TVIS10020572
Fusion event
HBV-chr9 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1117
End
2213
Orient
+
Integrated sequence
TTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTC
Host Sequence
Chromosome
chr9
Cytoband
q34.2
Reference genome
GRCh37/hg19
Start
137029056/134163934 (Hg38)
End
137030104/134164982 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7a-1/Upstream/1111875; hsa-mir-126/Downstream/214429;
Nearest TSS
ENST00000422679/Upstream/27846; ENST00000608264/Downstream/3787;
Nearest CpG islands
chr9-CpG: 163/Target, None/Upstream, None/Downstream
Nearby gene
WDR5(-3962) ; RNU6ATAC(+506) ;
Upstream sequence
tgctatgatactcagtgtacaaaaccttaaaaccatcaaaagtctatatacctacatagtaaacatataaaaattatgaatggggaggatatgaccaact
Downstream sequence
GGACTTCCGGACGCGGCCCTGCCCCGGGAACTGCGGGTGTTCAGGACCCTGTGGTGCGCGGGACGCCGCCCGCGCATGCGCCGCGCCGGCTCAGCCCCGT
Target sequence
CGACCGAGGCGCCCTCGGGAGACGGGCCCTGTCGGGTGTCGAGACGCGAACACGACCCAATGCCAAGAACGGGCGGTGAAGATGAACGGAAAAGCCCCAAGCAGCGGCGGAACGGCGCGCCCGTGCACAAGTGCGACCCGCGCCCGTGTCCCAAGGAAAGAAGATAAAAGATAAAACGAAAAATGCCCCGGGGCTTTgcggtgactcacgcctgtaatccccgcactttgggaggccgaagcgggcggatcacct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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