VISDB Viral Integration Site DataBase

VIS ID

TVIS10020574

Fusion event

HBV-ODF2 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1112

End

2208

Orient

+

Integrated sequence

GGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTC

Chromosome

chr9

Cytoband

q34.11

Reference genome

Start

End

131251603/128489324 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-375 ; hsa-mir-26b-5p

Nearest miRNA

hsa-let-7a-1/Upstream/95562; hsa-mir-12126/Downstream/1380281;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/31157, chr9-CpG: 47/Downstream/15235

Upstream sequence

agaccagtttacaaagctgttgtcataatccaagtaagaacgactaagggaactaaggtactgatagtggaaattaaagaaaagtCCAGTTATTAGAAAG

Downstream sequence

cacagatcctagaattttcataaagtgaatatactttgtccatcactcactctgattgaaccttgcctgcaccctagtgacctttcttgttactaatacc

Target sequence

tagccaggcgtggaggcatgcgcctgtagtcccagctactcgggaggctgagttgggagaatcgcttgagcctgggaggttgaggctgtggtgagccgagatcgccccactgcactccagcctggaaaacagagagagactctgtgtcaaaaaagaaaagaaagcctggattcaagtccttactctgctgcttcctggctgtaggacctgagtgaaaaacattccatgcctcttccttaggtagaggaaatgagg