VISDB Viral Integration Site DataBase

VIS ID

TVIS10020575

Fusion event

HBV-CMPK1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1109

End

2205

Orient

+

Integrated sequence

CAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACAC

Chromosome

chr1

Cytoband

p33

Reference genome

Start

End

47821366/47355694 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-374b-5p ; hsa-mir-590-3p ; hsa-mir-215-5p ; hsa-mir-34a-5p ; hsa-mir-10a-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-484 ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-130b-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-10b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520a-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-302e ; hsa-mir-4725-5p ; hsa-mir-143-3p ; hsa-mir-4461 ; hsa-mir-219b-3p ; hsa-mir-4708-5p ; hsa-mir-4770 ; hsa-mir-1273f ; hsa-mir-6088 ; hsa-mir-7852-3p ; hsa-mir-101-5p ; hsa-mir-874-3p ; hsa-mir-18b-3p ; hsa-mir-3157-3p ; hsa-mir-3177-5p ; hsa-mir-3171 ; hsa-mir-494-3p ; hsa-mir-4703-3p ; hsa-mir-4691-3p ; hsa-mir-944

Nearest miRNA

hsa-mir-12136/Upstream/2809094; hsa-mir-101-1/Downstream/3704143;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/19892, chr1-CpG: 129/Downstream/60530

Upstream sequence

TCAAAGCGAAAGGAAGCACAAGCAGTAGGGGGAGGAGGTGTAAATTTCCCCCGCGGTCCCTTGGAACTGTGAACATTTGCAGATTCCCCAAGCCCTCCCG

Downstream sequence

ttcccgagttcaaatgattctcatgcctcagccccgcaagtagctgggactacaggcatgtaccaccacacctggctaatttttgtatttttagtagaga

Target sequence

catatcggaacatacagatagttctacttcataatatgcacaatagtttacttagccattcctatattggtggaagtttagatttgttttggtggacatagacatttgtttacaaaagacactgctgtaaacattcatgtacatatgtctttgtgcacatgtgcaacagtgccataactcctagaaatggaattactgagtcaaagtttgagcaaacttaaacttggattgaataaacttaaataatttgcccaa