Basic Information
VIS ID
TVIS10020576
Fusion event
HBV-chr19 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1106
End
2202
Orient
+
Integrated sequence
TTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATA
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
11676286/11565471 (Hg38)
End
11677334/11566519 (Hg38)
Orient
+
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-1181/Upstream/69849; hsa-let-7e/Downstream/1137082;
Nearest TSS
ENST00000633603/Upstream/6010; ENST00000587939/Downstream/10424;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/6042, chr19-CpG: 49/Downstream/12092
Nearby gene
ELOF1(-6235) ; ZNF627(+9189) ;
Upstream sequence
cgatctcagcttactacaacctccacctcctgggttcaagcaattctcctgcctcagcctcccaagtagcggggattacaggcgcgtgccaccacgcctg
Downstream sequence
ctggtgtggtggctatgcctgtaatcccagcattttgggaggccaaagtgagaggatcacttgaggacaggagttcaagaccagtttgggcaacctaggg
Target sequence
atattgtttttgtatttgtttctactttctctcttgatatttTCCCGAGCCAATGTTTTGTTTTGGtttttttttatttttttttattttagagataggatctcactccatcatccaggctcaggctggaatgccgtggtgtgatcattgctcactgtagcctccagcacctgggctcgagggatcttcccacctcagcctcctaaatagctggaactacaggcgtacacctccatgcctggttaatttatgtat
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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