Basic Information
VIS ID
TVIS10020578
Fusion event
HBV-chr8 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1104
End
2200
Orient
+
Integrated sequence
ACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAA
Host Sequence
Chromosome
chr8
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
109586413/108574184 (Hg38)
End
109587461/108575232 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-12123/Upstream/4089719; hsa-mir-10400/Downstream/4068261;
Nearest TSS
ENST00000518652/Upstream/100333; ENST00000521504/Downstream/5830;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/130150, chr8-CpG: 36/Downstream/211968
Nearby gene
LOC101060000(-1051) ;
Upstream sequence
TTACACAGCTATCAGAGCAAGAGGGAGGTTAGTAAAAGCTGGTGGACCTTAAAGTTTCTCTACTTTTGCAAGTGTAAAAACTGGGGTAAAGATAGAGTTT
Downstream sequence
AAACTTTCTTTTATTTGTGGTGGTGAGCAGAGGCAAGAAGGAGGGGAAAGGCCTGCAGTAGATGAACCATCCCCTGAGATTTTCTAGGAGGGGCCACTAA
Target sequence
atcaggcattagcttctcataagaagcatgatgcctagatccctcacatgtgcagttcacagtagggtccacgttcctatgagaatctaatactgcactgatctgacaggagatggaactcaggagatattgccagcaatggggaatggctgtaaatacagatgatgctttgctggcttgcccactgctcacctcctgctgtgtgacccagttcctgcaggccacagactgctacaggtcagtggcccgagagtt
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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