ART3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10020581
Fusion event
HBV-ART3 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1106
End
2202
Orient
+
Integrated sequence
TTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATA
Host Sequence
Chromosome
chr4
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
76953361/76032208 (Hg38)
End
76954409/76033256 (Hg38)
Orient
+
Location type
Intronic
Target gene
ART3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-122-5p
Nearest miRNA
hsa-mir-12113/Upstream/9755280; hsa-mir-1243/Downstream/540312;
Nearest TSS
ENST00000502981/Upstream/8711; ENST00000510423/Downstream/2941;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/41109, chr4-CpG: 54/Downstream/114657
Upstream sequence
CTTGTTGTCTTGCTTGTTTAATAATGGAACATATAGCACTTTATTTAAAATAGATTAAATTTGCTATTAAAGATCCATGAAAAATATAAAGTTATttaaa
Downstream sequence
GTCATGCTACAGGAACACACATTGGGAAGACACTACTGTAAGACTTTCATTGTTTCTCCTGCTGCTGCCAGGCTTGAAATAATTTTCTTACTAATAGTAT
Target sequence
ACTCTGTGAAttttttttttttttgaggcaggcttttgcccaggctggagtgcagtggtgtgatcacagctgactgcagcctcaacctcccagacccaagtgatccatccacctcagcttcccaagtagctgaggttacaggcatgtgccaccatacccagctaattttcctattttttatagagatgaattttcgctatgttgcccaagctagtcttgaactcctgggcttaagccattcacctatgttggtct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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