Basic Information
VIS ID
TVIS10020582
Fusion event
HBV-chr22 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1093
End
2189
Orient
+
Integrated sequence
CTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCC
Host Sequence
Chromosome
chr22
Cytoband
q13.31
Reference genome
GRCh37/hg19
Start
47734197/47338447 (Hg38)
End
47735245/47339495 (Hg38)
Orient
+
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-let-7a-3/Upstream/1224679; hsa-mir-12114/Downstream/934869;
Nearest TSS
ENST00000624155/Upstream/422405; ENST00000434707/Downstream/6074;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/124875, chr22-CpG: 25/Downstream/869850
Nearby gene
LOC339685(+7124) ;
Upstream sequence
AACCTGTGAGTCTTTAAATTCTATTTTTAGGCTTCTGTGTTCTTCTCAtttttctaccttgatccatcatggcctgagaaagatgaattaaaatttccta
Downstream sequence
CTGCGTTTCATTGGTGCTTGTATCTGTCTCCGTCCTGCTTTCAGTTGGGTTTACCTTTCGGATATGATTTTCTGGTTTCCTCATATTTTTTCCTGAGCTT
Target sequence
ctctaaagtatccctgctgcttcttgtattttctgaacttgagcactatcgaagttgatgttacattatgttgtgctactatctataattgctagattttgtggattgcaccctttatcattctaaagtgactttttgttctatagaatgccttttgtcccaaaatacagcctgtctgatattgattgttggccctgcattttaaaaatgcatttgcctttcgtgcttttatctttaacctctctgagtcgcttt
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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