Basic Information
VIS ID
TVIS10020583
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1108
End
2204
Orient
+
Integrated sequence
ACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACA
Host Sequence
Chromosome
chr7
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
17012921/16973297 (Hg38)
End
17013969/16974345 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-339/Upstream/9906252; hsa-mir-10399/Downstream/1152875;
Nearest TSS
ENST00000635602/Upstream/56938; ENST00000475440/Downstream/157845;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/121834, chr7-CpG: 107/Downstream/324283
Upstream sequence
tatctaaaagtgggcatatcatctcagtcataatggtaaggatctttctttgcagtaagctgttcttacggaacacaaagcattagggagttttcttaat
Downstream sequence
tactcatgaatgactggtagatatatgaactgttacagcatttgggacaatatatttagtggaacctcttaaatttagacacacacatacctttcatttt
Target sequence
aacagatgatttctatcaaaatacaaattatcaaaaattgatccaagaaaataatacaatactcaaagtaatttccttagaagatacaggaatatcattaaaaatttcatcaagaccagatggtcttaccactaaattttatgtgcaaagttaaaaaatgtttaaaccatatattgtgttgtgttacttaaaaatctcccaggacgtagaaaaagaagaaaatttctctaattaatttaattaagATATTTATga
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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