Basic Information
VIS ID
TVIS10020584
Fusion event
HBV-chr21 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1087
End
2183
Orient
+
Integrated sequence
CTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAG
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
45418198/43998317 (Hg38)
End
45419246/43999365 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7c/Upstream/388328; hsa-mir-6815/Downstream/1478901;
Nearest TSS
ENST00000624081/Upstream/26914; ENST00000380221/Downstream/12954;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/15356, chr21-CpG: 157/Downstream/12400
Nearby gene
LOC105372829(-806) ;
Upstream sequence
ggtggcaatgggggctgatgaggatcttctacttacctttgccccgcaagggggtgtccctcttgactcccagcagattcaatccaggtggaggagatgg
Downstream sequence
cctggcaccactgattggagacactgtcctttttcGGAGTAGTGAATACACTCCCATCGTTCAGACATTGCAGTTATCCAGCCCAGTGCAAAGGAGAGGC
Target sequence
agctgcagggccaggtgcctcgacactgccctccaatttgaagggcttccaatcaccaaaggtgtgtcttttctccctgctgcgcttcacattctccctctgacactccagtcaaatcttagctatttattcattgtcttggtcctttcttgtggaggacaagtgccaggggtctctagtcagccaccctgatgacattatgctctgtggttttaatttgaattttcctgcaatgcaaataattagtcatgctta
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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