Basic Information
VIS ID
TVIS10020585
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1081
End
2177
Orient
+
Integrated sequence
AGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACA
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
118542934/117785358 (Hg38)
End
118543982/117786406 (Hg38)
Orient
+
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/4063990; hsa-mir-10b/Downstream/9637131;
Nearest TSS
ENST00000437798/Upstream/1970695; ENST00000489933/Downstream/17768;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2622169, chr2-CpG: 48/Downstream/28130
Upstream sequence
ACATGTGCAAATGCCCACAGGGGTGTGCGGGCGAAACCCACCTCCAGGCCCCATGTGCTCATGTCCTCCAGGTAGGTGCGTGTTGTCTTTCCCATAGAGG
Downstream sequence
CAACCCAGAAAAGGAGTTACTCAGTGGCCTATTAGAGTTAGAATACTCTACCCAGCCAGTTGAGATTGATCTAATAAACCACCTCTCTAAAGCTACCTGA
Target sequence
GTCTTTTAGAAGggctggtcacagtggctcatgcctgtaatcccagcacttctggaggctgaggaaggaggattacttgatcccaggagtacaagaccaggctaagcaacatagggagaccccatctctacaaaacattttttaaaattagcctggtgtgatagcactcacctgtggtcctagagactcagcaggctgagacgggagaatcacttgagcccaggaggtcaaggctgcagtgaaccatgatcatgc
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
Curate