Basic Information
VIS ID
TVIS10020587
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1184
End
2280
Orient
+
Integrated sequence
TGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGC
Host Sequence
Chromosome
chr11
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
91208490/91475324 (Hg38)
End
91209538/91476372 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10392/Upstream/606122; hsa-let-7a-2/Downstream/2257302;
Nearest TSS
ENST00000527297/Upstream/317241; ENST00000577699/Downstream/317990;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1252134, chr11-CpG: 204/Downstream/748097
Upstream sequence
ctgcaggcatatcttgtgatacataaactacaggcaagaaaaatatgtcagattgccactgcctgcttccacgttaactgaagatgctttgggcctaaca
Downstream sequence
aatacagctgaaaaatcacttcaaaaactctataatacaaattgcaaatattaagagcagaatcaatcaagcagaggaaggaatctcagagctcaaaaac
Target sequence
gctcatgaaaatgggccaatctgatctgagtgttcccctgtctgctggatttccctgaggccccagtctggttgttcttgggggccatcatccgaggtccttcaccagctgacgacacctaactatcagagagcaccacaaaaccagtctccactaacatgtacccatccacgtgcaaccccttcccaacacagccttctctcacatgcactcacccagagtgccccccatactggtttgccagcatatatacct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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