Basic Information
VIS ID
TVIS10020590
Fusion event
HBV-chr16 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1135
End
2231
Orient
+
Integrated sequence
TAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTG
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
33845806/34043339 (Hg38)
End
33846854/34044387 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1225/Upstream/3149354; hsa-mir-11401/Downstream/119191;
Nearest TSS
ENST00000527434/Upstream/66993; ENST00000319817/Downstream/115649;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/27813, chr16-CpG: 111/Downstream/5728
Upstream sequence
ACCACGGCTAAAAATCTCTTCCTGAACCATTCAGAAAATGCAACAGCGAAAGACATTGCCCCTACTTTAACACTCTATGTGGGGAAAAAGCAGCTTGTAG
Downstream sequence
ctaaattgtttcctctatatagatgctgaaatcctaaccactgaatatgacctcattaggaaacaggttctttgcaggtgatcaagttaagataaaatca
Target sequence
atcgagaccatcctggctaacacagtgaaaccccgtctctactaaaaatacaaaaaattagccgggcgtgatggcaggcgcctgtagtcccagctactcgggaggctgaagcagaagaatggcatgaagctgggagatggagcttgcagtgagcggagattgtgccactgcactccagcctgggagacaaagggagactcagtctcaataataataataatgataatatgtgcataatgtatttctgagtatttg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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