Basic Information
VIS ID
TVIS10020591
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1135
End
2231
Orient
+
Integrated sequence
TAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTG
Host Sequence
Chromosome
chr18
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
15203868/15203869 (Hg38)
End
15204916/15204917 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-3156-2/Upstream/373627; hsa-mir-1-2/Downstream/6478601;
Nearest TSS
ENST00000575820/Upstream/39402; ENST00000579454/Downstream/5749953;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/5559, chr18-CpG: 62/Downstream/125392
Nearby gene
LOC112268217(-5617) ;
Upstream sequence
tatgagagaaagtctgttctgtgccttgtttctagcttctggtggtttagtggcagtctttggcattccttggctactctcttccctcataatcacatgg
Downstream sequence
gggactacaggcgcccgccatcacgtccagctaattttttgtatttttagtagagacgggtttcattgtgttagtcaggatggtctcgatcttctggcct
Target sequence
ttgaattcaggctcatctgattttatcttaacttgatcacctgcaaagaacctttttcctaatgagatcatattcagtggttaagatttcagcatctatatagaggaaacaatttagctcatatctgtgcatacatgattgtaatagctatgtcttccaaaagcgttgacccccttgttactactgtataaatttttaaaatcctattcacatttttaatagtctctatcgtgttttatgagtataatgggttca
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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