Basic Information
VIS ID
TVIS10020595
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1125
End
2221
Orient
+
Integrated sequence
AAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTG
Host Sequence
Chromosome
chr7
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
64980515/65515602 (Hg38)
End
64981563/65516650 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
LOC101929322 ; LOC105375333
Nearest miRNA
hsa-mir-1183/Upstream/836426; hsa-mir-10399/Downstream/1597672;
Nearest TSS
ENST00000635602/Upstream/52531; ENST00000434382/Downstream/356617;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/5521, chr7-CpG: 102/Downstream/37653
Upstream sequence
CATAACCTTTTAGTGTCCCAGTTTATAGGAGTGGAGCTGTCTGCTGTTAGGTTCTTCACTGTGGAAAGGGTGATTTCTGCATTTTCTTTTCTTCTCCCTG
Downstream sequence
cggcttcatgccattcttctgcttcagcctcccgagtagctgggactacaggcgcccgccatcacgcccggctaattttttgtatttttagtagagacgg
Target sequence
ttttataaggacatcagtcatattgaattcaggctcatctgattttatcttaacttgatcacctgcaaggaacctatttcctaatgaggtcatattcagtggttaggatttcagcatctgtatagaggaaacaatttagctcaAATCTgtgcatacatgattgtaatagctatgtcttcctaaagcgttgacctccttattcctacaataaaaatttttaaaatcctattcacatttttaatagtctatattgtg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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