Basic Information
VIS ID
TVIS10020597
Fusion event
HBV-chr17 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
853
End
1949
Orient
+
Integrated sequence
GTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTTGGGGTACTTTACCGCAGGAACATATTGTACAAAAACTCAAGCAATGTTTTCGAAAATTGCCTGTAAATAGACCTATTGATTGGAAAGTATGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGCTATCCTGCCTTGATGCCTTTATATGCATGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTT
Host Sequence
Chromosome
chr17
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
25282916/26955890 (Hg38)
End
25283964/26956938 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1180/Upstream/7611316; hsa-mir-10226/Downstream/336972;
Nearest TSS
ENST00000595228/Upstream/4263056; ENST00000583786/Downstream/42987;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/180077, chr17-CpG: 114/Downstream/5523
Upstream sequence
GGAGCTACTGCTGTCTGCCTGGAGACAAGCGAGTTAAGAATAACTTTGCAGAGGCTGAGCTTTACAGGCCTAGCCATCCTGAAATAGCTGAGACATGATC
Downstream sequence
atttgagtagagggagacatacacacagggagggtaccatgtgattatgagggcagagattagccaaggaatgccaaagactgccactaaaccaccagaa
Target sequence
ccaggaggtcgagccgtgatcgcgaccgtgtactccagcctgggcggcagatctagaccctatctccaaaaaaaaaaaaaaaaaaaagagaaaagaAAAAAGAGAAAGAAAAACTTTGACCTGAAGACACGCCAATGCTCTTCAGCCTGTGTAGGCAGGTGTGACCCCCGTGCGGGGGTCCCGGGCGCTGTGCCCACAGAACAGGGTCTGACCCAGCACGCGGACGGAACCTTATTTTAACCCGAGACACAAACG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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